产品详情 |
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Antigenic Specificity | Programmed Cell Death 1 Ligand 1 (PD-L1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | 3.00 mg/ml |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Programmed Cell Death 1 Ligand 1 Antibody is a Rabbit Polyclonal antibody against PD-L1 (CD274). Programmed cell death ligand 1 (CD274, or B7-H1, PD-L1) is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens. It also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. |
Immunogen | Recombinant protein of human CD274. |
Other Names | CD274; CD274 Molecule; CD274 Antigen; B7 Homolog 1; Programmed Cell Death 1 Ligand 1; PDCD1 Ligand 1; PDCD1LG1; PDCD1L1; PDL-1; PD-L1; B7H1; PDL1; Programmed Death Ligand 1; B7-H1; B7H-1; B7-H |
Gene, Accession # | CD274, Gene ID: 29126, SwissProt: Q9NZQ7 |
Catalog # | abx001385 |
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Order / More Info | Programmed Cell Death 1 Ligand 1 (PD-L1) Antibody from ABBEXA |
Product Specific References | n/a |
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