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| Product Name | Malate Dehydrogenase Activity Colorimetric BioAssay™ Kit (MDH) |
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| Description | Malate Dehydrogenase (MDH) (EC 1.1.1.37) is an important enzyme which reversibly converts L-malate into oxaloacetate in the presence of NAD. In eukaryotic cells, malate dehydrogenase has 2 isoforms: MDH1 and MDH2. MDH1 is cytosolic and participates in the malate-aspartate shuttle, which transports malate into mitochondria for utilization in ATP generation whereas MDH2 is a mitochondrial enzyme and part of the citric acid cycle. MDH activity is increased in some neurodegenerative diseases such as Alzheimer's disease, and abnormal MDH activity in serum can serve as a diagnostic tool for severe liver damage (e.g. Hepatocellular carcinoma). Sample Type: Animal tissues such as liver, heart, muscle, etc. Cell culture: Adherent or suspension cells. Mitochondria. Intended Use: For use in the measurement of malate dehydrogenase activity in various tissues/cells and for analysis of the citric acid cycle and malate-asparate shuttle. Sensitivity: The assay can detect Malate Dehydrogenase (MDH) Act |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 220018 |
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| Order / More Info | Malate Dehydrogenase Activity Colorimetric BioAssay™ Kit (MDH) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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