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| Antigenic Specificity | Caspase-8 subunit p18 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 750 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase-8 subunit p18 Antibody, Alexa Fluor® 750 Conjugated. • Target Background: Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and C |
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| Immunogen | KLH conjugated synthetic peptide derived from human Caspase-8 subunit p18. Immunogen Range: 217-244/479 |
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| Other Names | CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; Caspase-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; CASP8 |
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| Gene, Accession # | Gene ID: 841, SwissProt: Q14790 |
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| Catalog # | bs-6463R-A750 |
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| Price | |
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| Order / More Info | Caspase-8 subunit p18 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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