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| Antigenic Specificity | Caspase-9 Thr125 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase-9 (Thr125) Polyclonal Antibody. • Target Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
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| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Caspase-9 around the phosphorylation site of Thr125. Immunogen Range: 100-150/416 |
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| Other Names | Phosphorylated, phospho-MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9 |
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| Gene, Accession # | Gene ID: 842, SwissProt: P55211 |
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| Catalog # | bs-3082R |
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| Price | |
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| Order / More Info | Caspase-9 Thr125 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Cetintas, Vildan Bozok, et al.(2016) Medicine (Baltimore). PubMed: 27787370 |
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