| Edit |   |
|---|
| Antigenic Specificity | Caspase-9 Ser196 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | Protein A purified |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | WB, IHC-P, IF(IHC-P) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Caspase-9 (Ser196) Polyclonal Antibody. • Target Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
|---|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human CASP9 around the phosphorylation site of Ser196. Immunogen Range: 180-220/416 |
|---|
| Other Names | Phosphorylated, phospho-MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9 |
|---|
| Gene, Accession # | Gene ID: 842, SwissProt: P55211 |
|---|
| Catalog # | bs-5241R |
|---|
| Price | |
|---|
| Order / More Info | Caspase-9 Ser196 Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|