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| Product Name | 96-well Cellular Senescence Assay (SA beta-Gal Activity) |
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| Description | Background: Normal primary cells proliferate in culture for a limited number of population doublings prior to undergoing terminal growth arrest and acquiring a senescent phenotype. This finite life span correlates with the age of the organism and with the life expectancy of the species from which the cells were obtained; such that the older the age or the shorter the life span, the less the ability of the cells to undergo population doubling. Senescent cells are characterized by an irreversibleG |
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| Size | 24 assays, 120 assays, 600 assays, |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168468 |
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| Order / More Info | 96-well Cellular Senescence Assay (SA beta-Gal Activity) from MYBIOSOURCE INC. |
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| Product Specific References | 1. Current Protocols in Molecular Biology, John Wiley & Sons Press.2. Campisi, J. (2000) In Vivo 14, 183-188.3. Dimri, G. P., X. Lee, G. Basile, M. Acosta, G. Scott, C. Roskelley, E. E. Medrano, M. Linskens, I. Rubelj, O. Pereira-Smith, M. Peacocke, and J. Campisi. (1995) Proc. Natl. Acad. Sci. USA 92:9363-9367.1. Lu, J. et al. (2014). SIRT1 counteracted the activation of STAT3 and NF-kappaB to repress the gastric cancer growth. Int J Clin Exp Med. 7:5050-5058.2. Malhotra, D. et al. (2010). Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res. 10.1093/nar/gkq212. |
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