| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Forkhead Box P3 (FOXP3) |
|---|
| Clone | 3G3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | IgG1 |
|---|
| Format | unconjugated |
|---|
| Size | 0.1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FACS),Western Blotting (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | FoxP3 (Forkhead box protein 3), a highly conserved forkhead/winged-helix transcription factor, plays a crucial role in maintaining immune homeostasis by governing the development and function of regulatory T cells. It is constitutively expressed at high level in CD25+ CD4+ Treg cells and at low level in a CD25- CD4+ Treg cell subset. Defects in gene encoding FoxP3 protein cause the scurfy phenotype in mice, and in human the IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome. |
|---|
| Immunogen | Full-length His-tagged recombinant murine FoxP3 |
|---|
| Other Names | foxp3|FOXP3|AIID|DIETER|IPEX|PIDX|XPID|JM2|scurfin|sf|RGD1562112 |
|---|
| Gene, Accession # | Gene ID: 50943,20371 |
|---|
| Catalog # | ABIN2749083 |
|---|
| Price | |
|---|
| Order / More Info | Forkhead Box P3 (FOXP3) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|