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| Product Name | Glypican-3, GPC3 Protein (Active) |
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| Description | MW: 67,049 Da. Recombinant full length human GPC3 protein.Glypican 3, GPC3 is a member of the glypican family that are heparan sulfate proteoglycans that bind to the exocytoplasmic surface of the plasma membrane through a covalent glycosylphosphatidylinositol (GPI) linkage. GPC3 gene contains 8 exons and encompasses approximately 500 kb. It encodes a putative extracellular proteoglycan, glypican 3, that is inferred to play an important role in growth control in embryonic mesodermal tissues i |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | ELISA (EIA), SDS-PAGE |
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| Other Names | [glypican-3; Glypican-3; glypican-3; proteoglycan GPC3; intestinal protein OCI-5; defective in Simpson-Golabi-Behmel overgrowth syndrome; glypican 3; Intestinal protein OCI-5] |
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| Gene, Accession, CAS # | GPC3, Gene ID: 25236, Accession: NP_036906.1 |
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| Catalog # | MBS355601 |
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| Order / More Info | Glypican-3, GPC3 Protein (Active) from MYBIOSOURCE INC. |
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| Product Specific References | 1. Pilia, G., Hughes-Benzie, R. M., MacKenzie, A., Baybayan, P., Chen, E. Y., Huber, R., Neri, G., Cao, A., Forabosco, A., Schlessinger, D. Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nature Genet. 12: 241-247, 1996. 2. Capurro, M. I., Xu, P., Shi, W., Li, F., Jia, A., Filmus, J. Glypican-3 inhibits Hedgehog signaling during development by competing with Patched for Hedgehog binding. Dev. Cell 14: 700-711, 2008. |
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