| 产品详情 |
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| Antigenic Specificity | ROR1 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases. |
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| Immunogen | Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells. |
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| Other Names | Neurotrophic Tyrosine Kinase; Receptor-Related 1 Ror1 Ntrkr1; NTRKR1; dJ537F10.1; ROR1; Tyrosine-protein kinase transmembrane receptor ROR1; receptor-related 1; receptor tyrosine kinase-like orphan receptor 1; MGC99659; neurotrophic tyrosine kinase receptor-related 1 |
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| Gene, Accession # | ROR1, Gene ID: 4919, SwissProt: Q01973 |
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| Catalog # | abx011486 |
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| Price | |
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| Order / More Info | ROR1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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