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Product Name | 15-PGDH Inhibitor (5-(4-(2-Cyclohexylethoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione) |
Description | Purity ~99% (HPLC). A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50=25nM). It is shown to increase PGE2 levels in IL-1b-stimulated A549 cells, dose-dependently, in the range of 0-20uM, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250g guinea pigs at 10ug and 20ug respectively. Synonyms: 5-(4-(2-Cyclohexylethoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione Formula: C19H23NO4S Molecular Weight: 361.5 Solubility: DMSO (100mg/ml, clear, pale yellow solution) |
Size | 10mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-(4-(2-Cyclohexylethoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione Formula: C19H23NO4S Molecular Weight: 361.5 Solubility: DMSO (100mg/ml, clear, pale yellow solution) Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
Gene, Accession, CAS # | n/a |
Catalog # | 217116 |
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Order / More Info | 15-PGDH Inhibitor (5-(4-(2-Cyclohexylethoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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