| 产品详情 |
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| Product Name | Recombinant Human 7,8-dihydro-8-oxoguanine triphosphatase (NUDT1) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 22.8kDa. Full Length of Mature Protein: 19-197aa. N-terminal 10xHis-tagged. Homo sapiens (Human). Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 2-hydroxy-dATP diphosphatase (EC:3.6.1.56); 8-oxo-dGTPase; Nucleoside diphosphate-linked moiety X motif 1 |
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| Gene, Accession, CAS # | NUDT1, UniProt: P36639 |
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| Catalog # | RPC20646 |
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| Order / More Info | Recombinant Human 7,8-dihydro-8-oxoguanine triphosphatase (NUDT1) from BIOMATIK |
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| Product Specific References | n/a |
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