| 产品详情 |
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| Antigenic Specificity | SAFB |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to SAFB. Scaffold attachment factor B (SAFB) is a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). SAFB is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. SAFB is thought to serve as a molecular base to assemble a transcriptosome complex in the vicinity of actively transcribed genes. SAFB is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene |
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| Immunogen | C-terminal region of human SAFB |
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| Other Names | Scaffold attachment factor B1, SAF-B, SAF-B1, HSP27 estrogen response element-TATA box-binding protein, HSP27 ERE-TATA-binding protein, HAP, HET, SAFB1 |
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| Gene, Accession # | UniProt: Q15424 |
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| Catalog # | orb131814 |
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| Price | |
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| Order / More Info | SAFB Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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