产品详情 |
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Antigenic Specificity | PCSK9 |
Clone | 1D05 |
Host Species | Human |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | ELISA, WB, Neut |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-PCSK9 Antibody (1D05). Recombinant Human Antibody (1D05) is capable of binding to PCSK9, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-PCSK9 mAb and CH1-3 region of human IgG2 and a light chain (LC) encoding VL from anti-PCSK9 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. 1D05-IgG2 dose-dependently inhibited PCSK9/LDLr binding in an in vitro TR-FRET assay with an IC50 of 3. 7 ± 0. 1 nM (n = 3).Can be useful in applications such as: Enzyme-linked Immunosorbent Assay, Western Blot, Neutralization |
Immunogen | Human proprotein convertase subtilisin/kexin type 9 |
Other Names | PCSK9; proprotein convertase subtilisin/kexin type 9; FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3; subtilisin/kexin-like protease PC9; neural apoptosis regulated convertase 1; convertase subtilisin/kexin type 9 preproprotein |
Gene, Accession # | Gene ID: 255738 |
Catalog # | PABZ-101 |
Price | |
Order / More Info | PCSK9 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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