| 产品详情 |
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| Antigenic Specificity | ZC3H8 |
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| Clone | OTI4H5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ZC3H8 Monoclonal Antibody (OTI4H5). Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. |
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| Immunogen | n/a |
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| Other Names | Fliz1, ZC3HDC8, zinc finger CCCH domain-containing protein 8, zinc finger CCCH type domain containing 8, zinc finger CCCH-type domain containing 8 |
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| Gene, Accession # | Entrez: 84524; Uniprot: Q8N5P1 |
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| Catalog # | MA5-26969 |
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| Price | |
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| Order / More Info | ZC3H8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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