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| Antigenic Specificity | APC2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC2 Polyclonal Antibody. Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a |
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| Immunogen | n/a |
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| Other Names | APCL; adenomatous polyposis coli like; adenomatous polyposis coli protein 2 |
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| Gene, Accession # | Entrez: 10297; Uniprot: O95996 |
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| Catalog # | PA5-67486 |
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| Price | |
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| Order / More Info | APC2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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