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| Product Name | Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric) |
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| Description | Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity, and tissue localization. MAO-A can oxidize primary amines such as serotonin and norepinephrine. MAO-A is a mitochondrial-bound enzyme that is ubiquitously expressed throughout the brain and other tissues. It has been implicated in panic, anxiety, and depression. Several MAO-A specific inhibitors such as clorgyline, brofaromine, toloxatone, tetrindole, etc. have been used as antidepressants, but their usage has been limited due to side effects. MAO-A Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-A inhibitors. The assay is based on the fluorometric detection of H2O2, one of the byproducts generated during the oxidative deamination of MAO substrate. |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Screening/studying/characterizing MAO-A inhibitors |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | Kit-2361 |
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| Order / More Info | Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric) from CREATIVE BIOMART |
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| Product Specific References | n/a |
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