| 产品详情 |
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| Antigenic Specificity | ACTN4 |
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| Clone | SN398 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human ACTN4 monoclonal antibody for IHC,WB. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008] |
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| Immunogen | A peptide corresponding to the N-terminus of human alpha-Actinin-4 |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 81, UniProt: O43707 |
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| Catalog # | CABT-BL8477 |
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| Price | |
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| Order / More Info | ACTN4 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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