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| Product Name | CARD18, 1-90aa, Human, His tag, E Coli |
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| Description | MW: 12.3 kDa (110aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 a |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Caspase recruitment domain-containing protein 18; ICEBERG; pseudo-ICE; uNQ5804] |
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| Gene, Accession, CAS # | CARD18, Gene ID: 59082, Accession: NP_067546 |
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| Catalog # | MBS204628 |
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| Order / More Info | CARD18, 1-90aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Humke E W., et al. (2000) Cell. 103:99-111.; Watson R W., et al. (1998) J Immunol. 161:957-962 |
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