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| Antigenic Specificity | CRK |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-CRK polyclonal antibody. This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
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| Immunogen | v-crk sarcoma virus CT10 oncogene homolog (avian) |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 1398, UniProt: P46108 |
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| Catalog # | FNab01981 |
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| Price | |
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| Order / More Info | CRK Antibody from FINETEST |
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| Product Specific References | n/a |
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