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| Product Name | Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) |
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| Description | MW: 20,917 Da. Purity >95% by SDS-PAGE. TIMP-1 is an inducible glycoprotein, which is synthesized by many different cell types. TIMP-1 binds in a reversible fashion to matrix metalloproteinases, with regions in the N-terminal domain binding to the MMP substrate-binding site. TIMP-1 also functions as erthyroid-potentiating activity via translocation to the nucleus and also in inhibiting apoptosis in B-cells. Recombinant TIMP-1 comprises a 184 amino acid fragment (24-207) corresponding to the matu |
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| Size | 0.01 mg, 0.1 mg, 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [TIMP-1; CLGI, EPA, EPO, HCI, TIMP, Erythroid-potentiating activity, collagenase inhibitor, metalloprotease inhibitor 1 precursor, tissue inhibitor of metalloproteases, Fibroblast collagenase inhibitor.] |
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| Gene, Accession, CAS # | TIMP-1, Gene ID: 7076, Accession: AAX47478.1 |
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| Catalog # | MBS343138 |
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| Order / More Info | Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) from MYBIOSOURCE INC. |
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| Product Specific References | Docherty AJ. et al., (1985) Nature. 318: 66-69. |
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