| 产品详情 |
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| Product Name | Norrie Disease (Pseudoglioma) (NDP) peptide |
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| Description | NDP activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. NDP plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. NDP acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | EVR2|FEVR|ND|evr2|fevr|xnorrin|Ndph|RGD1563968 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN937500 |
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| Price | |
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| Order / More Info | Norrie Disease (Pseudoglioma) (NDP) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 产品资料 |
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