| 产品详情 |
| Edit |   |
|---|
| Product Name | Raphin 1 |
|---|
| Description | Inhibitor of the regulatory subunit PPP1R15B of protein phosphatase (Kd = 33 nM). Displays >30-fold selectivity for PPP1R15B over PPP1R15A. Inhibits PPP1R15B-mediated dephosphorylation and protein synthesis in vitro. Induces transient reduction in protein synthesis in brains of wild type mice after single dose. Decreases SDS-insoluble huntingtin assemblies and nuclear inclusions in a mouse model of Huntington's disease. Orally bioavailable and brain penetrant. Purity 98%. MW (observed): 231.08 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (2E)-2-[(2,3-Dichlorophenyl)methylene]hydrazinecarboximidamide |
|---|
| Gene, Accession, CAS # | CAS: 2022961-17-5 |
|---|
| Catalog # | 6760/50 |
|---|
| Price | |
|---|
| Order / More Info | Raphin 1 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|