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| Product Name | Oncostatin M (OSM) (AA 26-252) (Active) protein |
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| Description | Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, including IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. In vivo, OSM is secreted from activated T cells, monocytes, neutrophils, and endothelial cells. OSM is related to LIF, and share a receptor with LIF in human. Human OSM can bind to gp130 and recruit OSM Receptor beta or LIF Receptor beta to form a ternary complex. OSM stimulates the growth of different types of cells, including megakaryocytes, fibroblasts, vascular endothelial cells, and T cells. On the other hand, OSM inhibits the proliferation of several cancer cell lines, such as solid tissue tumor cells, lung cancer cells, melanoma cells, and breast cancer cells.Recombinant human Oncostatin M (rhOSM) produced in E. coli is a single non-glycosylated polypeptide chain containing 228 amino acids. A fully biologically active molecule, rhOSM has a molecular mass of 25.9 kDa analyzed by reducing SDS-PAGE. Synonyms: OSM |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | OSM|OncoM |
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| Gene, Accession, CAS # | Gene ID: 5008 |
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| Catalog # | ABIN2018292 |
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| Order / More Info | Oncostatin M (OSM) (AA 26-252) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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