| 产品详情 |
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| Product Name | EML-425 |
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| Description | EML-425 is a potent, reversible and non-competitive dual CBP and p300 inhibitor (IC50 values are 1.1 and 2.9 µM, respectively). EML425 induced a marked and time-dependent reduction in the acetylation of lysine H4K5 and H3K9, a marked arrest in the G0/G1 phase and a significant increase in the hypodiploid nuclei percentage in human leukemia U937 cells. Cell-permeable. MW: 440.49. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-[(4-Hydroxy-2,6-dimethylphenyl)methylene]-1,3-bis(phenylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione |
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| Gene, Accession, CAS # | CAS: 1675821-32-5 |
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| Catalog # | B1882-5 |
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| Order / More Info | EML-425 from BIOVISION, INC. |
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| Product Specific References | n/a |
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