| 产品详情 |
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| Product Name | Zotarolimus |
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| Description | Purity >98% by HPLC. Zotarolimus is a semi-synthetic derivative of Sirolimus that acts as an immunosuppressant. Zotarolimus displays meachanism similar to sirolimus in having high-affinity binding to the immunophilin FKBP12 and comparable potency for inhibiting in vitro proliferation of both human and rat T cells. In vitro, zotarolimus inhibited FKBP-12 binding (IC50 = 2.8 nM) and potently blocked smooth muscle cell (IC50 = 2.9 nM) and endothelial cell (IC50 = 2.6 nM) proliferation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonic Acid, L 758298 |
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| Gene, Accession, CAS # | CAS: 221877-54-9 |
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| Catalog # | LS-H3559 |
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| Price | |
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| Order / More Info | Zotarolimus from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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