| 产品详情 |
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| Product Name | (Z)-PUGNAc |
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| Description | Purity >95%. Proteins can be modified post-translationally by the addition of O -linked N-acetylglucosamine (O -GlcNAc). Nuclear cytoplasmic O -GlcNAcase and acetyltransferase (NCOAT) is a Beta-N-acetylglucosaminidase that removes GlcNAc from O -glycosylated proteins. PUGNAc is a (phenylcarbamoyl)oxime analog of GlcNAc that reversibly inhibits NCOAT (Ki = 40-110 nM). It also less potently inhibits other hexosaminidases and exochitinases. (Z)-PUGNAc is a stereoisomer of PUGNAc that is a more potent inhibitor of NCOAT than the (E) isomer, both in vitro and in cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1Z)-d-lactone-2-(acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-gluconimidic acid |
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| Gene, Accession, CAS # | CAS: 132489-69-1 |
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| Catalog # | LS-H5695 |
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| Price | |
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| Order / More Info | (Z)-PUGNAc from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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