| 产品详情 |
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| Product Name | Z-VAD-FMK (Cell permeable) |
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| Description | Purity >95% by HPLC. Cell permeable, non-selective broad-spectrum caspase inhibitor. Binds irreversibly to the catalytic site of caspase proteases. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Potent inhibitor of caspase-1 activation in NLRP3/NALP3-induced cells. Used in apoptosis and inflammasome studies. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Benzyloxycarbonyl-Val-Ala-DL-Asp(OMe)-fluoromethylketone, pan-Caspase Inhibitor, Z-VAD(OMe)-FMK, Z-Val-Ala-DL-Asp(OMe)-fluoromethylketone |
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| Gene, Accession, CAS # | CAS: 187389-52-2, 634911-81-2 |
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| Catalog # | LS-H531 |
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| Price | |
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| Order / More Info | Z-VAD-FMK (Cell permeable) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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