| 产品详情 |
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| Product Name | LFM-A13 |
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| Description | Purity >98% by NMR, TLC. LFM-A13 is a selective inhibitor of Bruton's tyrosine kinase (BTK) - IC50's = 2.5 uM (recombinant BTK) and 17.2 uM (human BTK). It has also been shown to inhibit Polo-like kinase (PLK) - IC50 = 61 uM for human PLK3. LFM-A13 displayed no activity (concentrations up to 278 uM) at JAK1, JAK3, HCK, EGFRK and IRK2 or CDK1-3, CHK1, IKK, MAPK1, SAPK2a and ten tyrosine kinases. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2Z)-2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide |
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| Gene, Accession, CAS # | CAS: 244240-24-2 |
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| Catalog # | LS-H14736 |
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| Order / More Info | LFM-A13 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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