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| Product Name | Recombinant Human Merlin (NF2) |
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| Description | 1-595aa, Full Length. MW: 73.7 kDa. Purity >85% as determined by SDS-PAGE. Probable regulator of the HippoSWH (SavWtsHpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the HippoSWH (SavWtsHpo) signaling pathway. May act as a membrane stabilizing protein |
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| Size | 0.05 mg (E-Coli), 0.05 mg (Baculovirus), 0.05 mg (Mammalian-Cell), 0.2 mg (Yeast), 0.1 mg (Baculovirus) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [merlin isoform 1; Merlin; merlin; neurofibromin 2; Moesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; Schwannomin] |
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| Gene, Accession, CAS # | NF2, Gene ID: 4771, Accession: NP_000259.1 |
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| Catalog # | MBS956203 |
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| Order / More Info | Recombinant Human Merlin (NF2) from MYBIOSOURCE INC. |
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| Product Specific References | Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2. Rouleau G.A., Merel P., Lutchman M., Sanson M., Zucman J., Marineau C., Hoang-Xuan K., Demczuk S., Desmaze C., Plougastel B., Pulst S., Lenoir G., Bijlsma E., Fashold R., Dumanski J.P., de Jong P., Parry D., Eldrige R. Thomas G. Nature 363:515-521(1993) |
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