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| Antigenic Specificity | B-Cell CLL/lymphoma 10 (BCL10) |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein A purified |
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| Size | 40 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bcl-10 is a 31,000 Da protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD 9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. |
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| Immunogen | i-NTA purified recombinant human BCL-10 expressed in E. coli strain BL21 (DE3) |
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| Other Names | BCL10|AI132454|BCL-10|C81403|CARMEN|CIPER|CLAP|ME10|cE10|c-E10|mE10 |
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| Gene, Accession # | Gene ID: 8915 |
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| Catalog # | ABIN1842488 |
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| Price | |
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| Order / More Info | B-Cell CLL/lymphoma 10 (BCL10) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 9989491, 11152471, 11259443 |
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