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Product Name | RSK2, Active |
Description | RSK2 is a member of the RSK (ribosomal S6 kinase) family that are growth factor-regulated serine/threonine kinases. RSK2 has been shown to mediate growth factor signaling via RAS and MAPK leading to the induction of CREB serine-133 phosphorylation and activation of gene expression (1). Mutations in RSK2 have been shown to be responsible for Coffin-Lowry syndrome (CLS) which is a X-linked disorder characterized by severe psychomotor retardation, facial and digital dysmorphisms, and progressive skeletal deformations (2). MW: 112.0 kDa. Purity ≥90% |
Size | 5 µg |
Concentration | 0.1mg/ml |
Applications | RUO |
Other Names | RSK, ribosomal protein S6 kinase, 90kDa, polypeptide 3, MAP kinase-activated protein kinase 1c |
Gene, Accession, CAS # | RPS6KA3, Gene ID: 6197, Accession: NM_004586. |
Catalog # | 7768-5 |
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Order / More Info | RSK2, Active from BIOVISION, INC. |
Product Specific References | n/a |
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