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| Product Name | 4-hydroxy Nonenal Mercapturic Acid |
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| Description | Peroxidation of common ω-6 PUFAs such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat.{7334} About two thirds of an administered dose of 4-HNE is excreted within 48 hours in the urine, primarily in the form of mercapturic acid conjugates.{8626} The C-1 aldehyde of 4-HNE is reduced to an alcohol in about half of these metabolites. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form γ-lactols and γ-lactones, respectively, producing at least 4 or 5 end urinary metabolites of 4-HNE in vivo. |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-HNE 4HNE b-cleavage .beta.-cleavage beta-cleavage urine enterohepatic circulation conjugates acids 4-hydroxynonenal 4-OH-nonenal |
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| Gene, Accession, CAS # | CAS: 146764-24-1 |
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| Catalog # | 32110-5 |
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| Order / More Info | 4-hydroxy Nonenal Mercapturic Acid from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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