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Product Name | Jasplakinolide |
Description | Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro. Also induces polymerization of actin monomers into F-actin in vivo. Shown to bind to F-actin competitively with phalloidin (Cat. No. 4535) (Kd ~ 15 nM). Exhibits antifungal and antiproliferative effects (IC50 = 35 nM for antiproliferative activity in PC3 cells). Cell permeable. Purity 97%. MW (observed): 709.67 |
Size | 100 ug |
Concentration | n/a |
Applications | n/a |
Other Names | Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl] |
Gene, Accession, CAS # | CAS: 102396-24-7 |
Catalog # | 2792/100U |
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Order / More Info | Jasplakinolide from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25679761, 25857312, 26244347, 26555617, 26867505 |
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