| 产品详情 |
| Edit |   |
|---|
| Product Name | SIRT5 (GST-tagged), Human recombinant |
|---|
| Description | The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins, which have been designated SIRT1-7. SIRT5 is located in the mitochondrial matrix and its functions are largely still being elucidated, however a few promising substrates have been studied. SIRT5 has been shown to deacetylate carbamoyl phosphate synthetase 1 (CSP1), activating the enzyme to catalyze the first step of the urea cycle. CSP1 is important in the detoxification of excess ammonia that can accumulate during fasting. Cytoch |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | NAD-dependent Deacetylase 5; SIR2-like Protein 5; SIR2L5; Sirtuin 5; Silent Information Regulator 5 |
|---|
| Gene, Accession, CAS # | SIRT5, Gene ID: 23408, Accession: Q9NXA8 |
|---|
| Catalog # | 7674-50 |
|---|
| Price | |
|---|
| Order / More Info | SIRT5 (GST-tagged), Human recombinant from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|