| 产品详情 |
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| Antigenic Specificity | TMEM66 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TMEM66 Polyclonal Antibody. Saraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions. |
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| Immunogen | n/a |
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| Other Names | FOAP-7, XTP3, HBV X-transactivated gene 3 protein, HBV XAg-transactivated protein 3, protein FOAP-7 |
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| Gene, Accession # | Entrez: 51669, 67887; Uniprot: Q8R3Q0, Q96BY9 |
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| Catalog # | PA5-24237 |
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| Price | |
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| Order / More Info | TMEM66 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25517631, 27068144, 27414851 |
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