| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | TMEM66 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 50 µl |
|---|
| Concentration | lyophilized |
|---|
| Applications | Western Blot: 1:500 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | TMEM66 Polyclonal Antibody. Saraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions. |
|---|
| Immunogen | n/a |
|---|
| Other Names | SOCE-Associated Regulatory Factor |
|---|
| Gene, Accession # | Entrez: 290796, 51669, 67887; Uniprot: Q6AYN2, Q8R3Q0, Q96BY9 |
|---|
| Catalog # | PA5-77334 |
|---|
| Price | |
|---|
| Order / More Info | TMEM66 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|