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| Product Name | Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 72.9kDa. Full Length: 1-518aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | RIP-like protein kinase 3; Receptor-interacting protein 3 |
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| Gene, Accession, CAS # | RIPK3, UniProt: Q9Y572 |
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| Catalog # | RPC23799 |
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| Order / More Info | Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) from BIOMATIK |
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| Product Specific References | n/a |
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