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| Product Name | Recombinant Human Receptor-type tyrosine-protein phosphatase C (PTPRC), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 76.8kDa. Extracellular Domain: 24-575aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Leukocyte common antigen |
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| Gene, Accession, CAS # | PTPRC, UniProt: P08575 |
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| Catalog # | RPC21884 |
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| Order / More Info | Recombinant Human Receptor-type tyrosine-protein phosphatase C (PTPRC), partial from BIOMATIK |
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| Product Specific References | n/a |
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