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| Product Name | Human cardiac troponin I (cTnI), phosphorylated |
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| Description | n/a |
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| Size | 0.1 mg, 0.5 mg, 1 mg |
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| Concentration | n/a |
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| Applications | TnI is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium sensitivity to striated muscle actomyosin ATPase activity.Cardiac isoform of TnI (cTnI) has two serine residues at positions 22 and 23 which could be phosphorylated by cAMP-dependent protein kinase (PKA) in response to beta-adrenergic stimulation of the heart. Modification of these serines results in the changes of mydegree Cardial contractility. About 50% of cTnI purified from human cardiac tissue is mono- or biphosphorylated.cTnI purified from human cardiac tissue was completely phosphorylated in vitro by catalytic subunit of PKA from bovine heart.TnI is suitable for use as a standard in immunoassay, immunogen for antiserum production. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | [cTnI] |
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| Catalog # | MBS664013 |
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| Order / More Info | Human cardiac troponin I (cTnI), phosphorylated from MYBIOSOURCE INC. |
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| Product Specific References | Search Troponin I references from PubMed. |
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