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| Product Name | PF 06409577 |
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| Description | Potent and selective allosteric activator of AMPK (EC50 values are 7 and >40000 nM for AMPKα1β1γ1 and AMPKα1β2γ1, respectively). Exhibits minimal off-target effects on a panel of receptors, ion channels, PDEs and kinases. Improves kidney function and reduces proteinuria in a preclinical model of diabetic nephropathy. Orally bioavailable. Purity 98%. MW (observed): 341.79 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid |
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| Gene, Accession, CAS # | CAS: 1467057-23-3 |
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| Catalog # | 6114/50 |
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| Price | |
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| Order / More Info | PF 06409577 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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