| 产品详情 |
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| Product Name | PF 06424439 |
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| Description | Potent and selective DGAT2 inhibitor (IC50 = 14 nM). Exhibits no significant activity at MGAT1-3 or DGAT1. Reduces triglyderide synthesis in human hepatocytes in vitro. Reduces plasma triglyceride and cholesterol levels in a rat dyslipidemia model. Orally bioavailable. Purity 98%. MW (observed): 536.05 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinylmethanone methanesulfonate |
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| Gene, Accession, CAS # | CAS: 1469284-79-4 |
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| Catalog # | 6348/5 |
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| Price | |
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| Order / More Info | PF 06424439 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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