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Product Name | PF 06465469 |
Description | Potent inhibitor of interleukin-2 inducible T cell kinase (ITK) (IC50 = 2 nM). Also exhibits inhibitory activity against Bruton's tyrosine kinase (BTK) (IC50 = 2 nM). Displays nanomolar potencies in a cell-based IP1 assay and human whole blood assay (IC50 values are 31 and 48 nM respectively). Purity 95%. MW (observed): 523.63 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (R)-3-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(3-methyl-4-(1-methylethyl))benzamide |
Gene, Accession, CAS # | CAS: 1407966-77-1 |
Catalog # | 4710/50 |
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Order / More Info | PF 06465469 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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