| 产品详情 |
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| Product Name | PF 477736 |
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| Description | Selective checkpoint kinase 1 (Chk1) inhibitor (Ki values are 0.49 and 47 nM for Chk1 and Chk2 respectively). Abrogates cell cycle arrest at S and G2-M checkpoints; sensitizes cells to DNA damage. Enhances docetaxel (Cat. No. 4056) efficacy in tumor cells and xenografts. Purity 99%. MW (observed): 419.48 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (R)-α-Amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]-cyclohexaneacetamide. PF-0044736 |
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| Gene, Accession, CAS # | CAS: 952021-60-2 |
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| Catalog # | 4277/10 |
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| Price | |
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| Order / More Info | PF 477736 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25994202 |
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| 产品资料 |
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