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Product Name | PF 573228 |
Description | Potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM). Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro. Purity 98%. MW (observed): 491.49 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone |
Gene, Accession, CAS # | CAS: 869288-64-2 |
Catalog # | 3239/50 |
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Order / More Info | PF 573228 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19716803, 20071540, 20639453, 20802517, 21442631, 21483797, 21884573, 22016182, 22157678, 22188814, 22402981, 22407215, 22900166, 23300082, 23446637, 23470625, 23693126, 24113189, 24227778, 24260297, 24523534, 24623723, 24863845, 25409876, 25422477, 25621765, 25779634, 26020477, 26291058, 26501082, 26569550, 26630674, 26728047, 26854061, 27152864, 27293031, 27402964, 27497669, 27519953, 28065575, 28406972 |
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