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| Product Name | PF 670462 |
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| Description | Potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor (IC50 values are 7.7 and 14 nM respectively) that displays > 30-fold selectivity over 42 other common kinases. Inhibits PER protein nuclear translocation (EC50 = 290 nM) causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo. Purity 99%. MW (observed): 410.32 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride |
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| Gene, Accession, CAS # | CAS: 950912-80-8 |
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| Catalog # | 3316/10 |
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| Order / More Info | PF 670462 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22434859, 24075994, 24076244, 24424021, 24612480, 25627785, 25798617, 25866393, 28125685, 28945225 |
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