| 产品详情 |
| Edit |   |
|---|
| Product Name | PF 8380 |
|---|
| Description | Potent autotaxin inhibitor (IC50 = 2.8 nM in isolated enzyme assay; 101 nM in human whole blood). Modulates lysophosphatidic acid (LPA) levels in vivo and in vitro by directly inhibiting autotaxin; reduces LPA levels both in plasma and at site of inflammation. Decreases leptin-induced MMP13 expression, in vitro. Orally available. Purity 97%. MW (observed): 478.33 |
|---|
| Size | 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 3,5-Dichlorobenzyl-[4-[3-oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]]piperazine-1-carboxylate |
|---|
| Gene, Accession, CAS # | CAS: 1144035-53-9 |
|---|
| Catalog # | 4078/25 |
|---|
| Price | |
|---|
| Order / More Info | PF 8380 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|