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| Product Name | PF 915275 |
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| Description | Potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki = 2.3 nM) that displays little activity at 11βHSD2 (1.5% inhibition at 10 μM). Inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro (EC50 = 15 nM) and has antidiabetic activity in vivo. Orally active. Purity 98%. MW (observed): 350.39 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide |
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| Gene, Accession, CAS # | CAS: 857290-04-1 |
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| Catalog # | 3291/10 |
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| Price | |
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| Order / More Info | PF 915275 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23927023, 30021644 |
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| 产品资料 |
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