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| Product Name | PF 8380 |
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| Description | Potent autotaxin inhibitor (IC50 = 2.8 nM in isolated enzyme assay; 101 nM in human whole blood). Modulates lysophosphatidic acid (LPA) levels in vivo and in vitro by directly inhibiting autotaxin; reduces LPA levels both in plasma and at site of inflammation. Decreases leptin-induced MMP13 expression, in vitro. Orally available. Purity 97%. MW (observed): 478.33 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,5-Dichlorobenzyl-[4-[3-oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]]piperazine-1-carboxylate |
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| Gene, Accession, CAS # | CAS: 1144035-53-9 |
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| Catalog # | 4078/5 |
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| Price | |
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| Order / More Info | PF 8380 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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