| 产品详情 |
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| Product Name | ABT-751 |
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| Description | A tubulin polymerization inhibitor; binds to the colchicine binding site on β-tubulin (Ki = 3.3 µM); inhibits tubulin polymerization in a concentration-dependent manner; inhibits growth of 26 human tumor cell lines (IC50s = 0.06-0.08 µg/ml); induces tumor regression in NB-1382 neuroblastoma, IRS56 rhabdomyosarcoma, and KT-6 Wilms mouse xenograft models at 100 mg/kg; induces tumor endothelial cell retraction and reduces tumor perfusion in a 9L rat glioma subcutaneous tumor model |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 857447-92-8 141450-48-8 ABT751 microtubule β-tubulin NB-1382 NB1382 IRS-56 KT6 9-L ABT-51 ABT51 E7010 E-7010 |
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| Gene, Accession, CAS # | CAS: 141430-65-1 |
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| Catalog # | 22935-50 |
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| Price | |
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| Order / More Info | ABT-751 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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