| 产品详情 |
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| Product Name | Endomorphin 1 (trifluoroacetate salt) |
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| Description | An endogenous neuropeptide and μ-opioid receptor agonist (Ki = 0.36 nM); selective for μ- over δ- and κ-opioid receptors (Kis = 1,506 and 5,428 nM, respectively); binds to mouse brain membranes and rat recombinant μ-opioid receptors expressed in CHO cells (Kis = 0.94 and 0.66 nM, respectively); inhibits forskolin-induced cAMP accumulation in CHO cells expressing rat recombinant μ-opioid receptors and in SH-SY5Y human neuroblastoma cells (IC50s = 9.33 and 19.1 nM, respectively); increases analgesia in a radiant heat tail-flick assay in mice following intracerebroventricular or intrathecal administration (ED50s = 4.75 and 0.726 µg, respectively); induces conditioned place preference in mice at 10 µg, i.c.v.; decreases gastrointestinal transit time in mice at 12 µg, i.c.v. |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Tyr-Pro-Trp-Phe-NH2 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 23280-5 |
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| Order / More Info | Endomorphin 1 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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